Elizabeth Wade, PhD candidate University of Connecticut Advisor: Chris Simon

Conboy, C. M., Spyrou, C., Thorne, N. P., Wade, E. J., Barbosa-Morais, N. L., Wilson, M. D., Bhattacharjee, A., Young, R. A., Tavare, S., Lees, J. A., Odom, D. T. (2007). Cell cycle genes are evolutionarily conserved targets of the E2F4 transcription factor. PloS One 2(10), e1061.

Odom, D. T., Dowell, R. D., Jacobsen, E. S., Gordon, W., Danford, T. W., MacIsaac, K.,Rolfe, P. A., Gifford, D. K., Fraenkel, E. (2007). Tissue-specific transcriptional

regulation has diverged significantly between human and mouse. Nature Genetics 39,

730-732.

Marson, A., Kretschmer, K., Frampton, G. M., Jacobsen, E. S., Polansky, J., MacIsaac, K. D., Levine, S. S., Frankel, E., von Boehmer, H., Young, R. A. (2007). Foxp3 occupancy and regulation of key target genes during T cell stimulation. Nature 445, 931-935.

Odom, D.T., Dowell, R. D., Jacobsen, E. S., Nekludova, L., Rolfe, P. A., Danford, T.

W., Gifford, D. K., Fraenkel, E., Bell, G. I., Young, R. A. (2006). Core transcriptional

regulatory circuitry in human hepatocytes. Mol Syst Biol 2, 2006 0017

Zhang, X., Odom, D. T., Koo, S. H., Conkright, M. D., Canettieri, G., Best, J., Chen, H., Jenner, R., Herbolsheimer, E., Jacobsen, E., et al. (2005). Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A 102, 4459-4464.

Name changed from Elizabeth S. Jacobsen to Elizabeth J. Wade in 2007

I am interested in the processes and patterns of speciation. My projects use phylogenetics, population genetics and development to understand speciation in cicadas (Hemiptera: Cicadidae).

My thesis project focuses on the hybridization and speciation of the New Zealand cicada genus Kikihia. There are eighteen different species pairs that hybridize in this genus. I am using microsatellites to investigate to what extent hybridization is occurring at each contact zone and what the effects on the species boundaries and genetics hybridization is having.

I am also investigating the phylogenetics of the species complex Cicadetta montana. This European species complex is comprised of at least eight cryptic species. I am using both mitochondrial and nuclear loci to determine what the species relationships are and to validate the bioacoustically determined species.

In addition, I’m working on the genetic switch between 13- and 17- year periodical cicadas (Magicicada spp.). By investigating the diapause and circadian rhythm genes I hope to identify the genetic life history switch in all seven periodical cicada species.

Doctor of Philosophy, expected June 2011

University of Connecticut, Storrs,CT

Advisor: Chris Simon, Ecology and Evolutionary Biology

Master of Liberal Arts, November 2006

Harvard University, Cambridge, MA

Advisor: Amy Wagers, Molecular Biology

Bachelor of Science, May 2001

Brandeis University, Waltham, MA,

Major: Biology

2008 Fall: Biology 108, Intro to Biology Lab, Botany and Evolution (for

Biology majors)

2008 Summer: Mentored Jeselyn Calderon through the NEA program

2008 Spring: Biology 102, Introduction to Biology Lab (for non-majors)

2007 Fall: EEB 244, General Ecology (Discussion group)

2007 Spring: Biology 107, Intro to Biology Lab, Molecular Biology and

Anatomy and Physiology (for Biology majors)

2006 Fall: Biology 107, Intro to Biology Lab, Molecular Biology and

Anatomy and Physiology (for Biology majors)

Evolution Meeting, June 2008, University of Minnesota, Poster: Phylogenetics of the cicada (Hemiptera: Cicadidae) species complex Cicadetta montana (Scopoli 1772) in Europe: molecular validation of bioacoustically determined species

Graduate Student Symposium, March 2007, University of Connecticut, Department of Ecology and Evolutionary Biology, Talk: Gene flow between multiple species in the New Zealand cicada genus Kikihia